Our new Very clear+ tissue clearing procedure is the only real process that delipidates samples with no alter in morphology and with nominal effect on structural integrity.

Megatome is often a vibrating microtome meant to area a wide variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform area profile, and minimal tissue damage and information loss.

Antibodies could get weeks to diffuse by way of just a few millimeters of tissue, using a steep labeling gradient from surface area to core.

Megatome is made for accuracy: the blade vibrates at a greater frequency and larger amplitude range than other microtomes, and features a unique deflection Command system.

SE uses a rotational electric powered subject to disperse hugely electromobile molecules (including antibodies or surfactant micelles) all through a porous sample with out damaging electrically billed constructions inside the tissue. This enables two-four working day clearing of intact organs,

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Megatome is a novel microtome that enables for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with negligible tissue hurt megatomi.com and information decline.

eFLASH is really a immediate tissue labeling approach that allows for uniform complete-organ staining in 20 rounds of labeling.

The SmartSPIM mild sheet microscope provides unparalleled resolution and acquisition pace throughout intact tissue volumes, though its modular structure permits you to enhance and personalize unique elements.

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Protect avoids the variability of hydrogel embedding and the data loss from PFA preservation, safeguarding specimens for various rounds of processing.

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Our novel Protect tissue preservation technique types intramolecular bonds making use of polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.